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目的探讨心肌肌钙蛋白Ⅰ(cTNI)在心肌梗死中的早期诊断价值及心肌再梗死中的应用。方法测定130例急性心肌梗死(AMI)发作时患者的血清cTNI和肌酸激酶同工酶(CK-MB)的浓度,并以120名健康体检者作对照。结果 AMI组发病早期血清cTNI和CK-MB水平与对照组相比差异有统计学意义,在AMI发作后2~10 hcTNI敏感度高于CK-MB,在AMI发作10 h的患者,若cTNI>20.0μg/L,心肌再梗死与cTNI有相关性。结论 cTNI在AMI早期诊断和预测再梗死中有一定应用临床价值。
Objective To investigate the early diagnostic value of cardiac troponin Ⅰ (cTNI) in myocardial infarction and its application in myocardial infarction. Methods Serum levels of cTNI and creatine kinase MB (CK-MB) in 130 patients with acute myocardial infarction (AMI) were measured and compared with 120 healthy controls. Results The serum levels of cTNI and CK-MB in the early onset of AMI were significantly different from those in the control group. The sensitivity of cTNI at 2 ~ 10 h after AMI was higher than that of CK-MB. In patients with AMI 10 h, cTNI> 20.0μg / L, myocardial infarction and cTNI are related. Conclusion cTNI has some clinical value in the early diagnosis and re-infarction of AMI.