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目的观察丙泊酚不同配伍在无痛胃镜中的镇痛效果和安全性。方法将300例要求行无痛胃镜流产的患者随机分为试验组(K组,丙泊酚联合利多卡因,n=150)及对照组(F组,丙泊酚联合芬太尼,n=150),观察注射部位疼痛、呼吸、循环变化和麻醉恢复时间等。结果两组有效率为100%,观察项目中F组注射部位疼痛、呼吸抑制发生率较高,定向力恢复时间较长,与K组比较,差异有统计学意义(P<0.05)。结论丙泊酚联合利多卡因静脉麻醉用于无痛胃镜,安全有效,减少了不良反应。
Objective To observe the analgesic effects and safety of different compatibility propofol in painless gastroscopy. Methods Three hundred patients with painless gastroscopic abortion were randomly divided into experimental group (group K, propofol combined with lidocaine, n = 150) and control group (group F, propofol combined with fentanyl, n = 150), observe the injection site pain, respiration, circulation changes and anesthesia recovery time. Results The effective rate of the two groups was 100%. The pain in the injection group, the higher incidence of respiratory depression and the longer recovery time of the directional force in the observation group were observed. The difference was statistically significant (P <0.05). Conclusion Propofol combined lidocaine intravenous anesthesia for painless gastroscopy, safe and effective, reducing adverse reactions.