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目的观察探讨冠心病快速心律失常急诊应用胺碘酮的临床效果,总结其临床价值。方法选取我院2009年3月至2011年3月108例冠心病快速心律失常患者,均给予胺碘酮治疗,对其临床病历资料进行回顾性分析,观察其治疗效果。结果 108例快速心率失常患者经胺碘酮治疗后,阵发性房颤的转复率最高,其次为室性早搏,明显高于其他原因的心律失常的转复率(χ2=47.48,44.60,P<0.05),差异具有统计学意义。出现不良反应7例,血压下降至90/60mmHg(1mmHg=0.133kPa)有5例,经调慢滴速及补充血容量半小时后血压回升;出现呕吐、恶心1例,经调慢滴速后自行缓解;出现窦性心动过缓1例,心率降低至50次/min,经减少药量20min后,心率回复至65次/min。结论冠心病快速心律失常急诊应用胺碘酮的临床效果显著,能快速缓解临床症状,不良反应较少,安全性高,值得在临床上合理推广应用。
Objective To investigate the clinical effect of amiodarone in the emergency treatment of tachyarrhythmia of coronary heart disease and to summarize its clinical value. Methods A total of 108 patients with coronary heart disease with tachyarrhythmia from March 2009 to March 2011 were enrolled in this study. All patients were given amiodarone. The clinical data of the patients were retrospectively analyzed and their therapeutic effects were observed. Results After the treatment of amiodarone in 108 patients with rapid arrhythmia, the recovery rate of paroxysmal atrial fibrillation was highest, followed by ventricular premature beats, which was significantly higher than that of other causes of arrhythmia (χ2 = 47.48, 44.60, P <0.05), the difference was statistically significant. There were 7 cases of adverse reactions, blood pressure dropped to 90 / 60mmHg (1mmHg = 0.133kPa) in 5 cases, by slow drip and blood volume after half an hour blood pressure rise; vomiting, nausea in 1 case, after the slow drip rate Self-remission; sinus bradycardia occurred in 1 case, heart rate reduced to 50 beats / min, after reducing the dose 20min, the heart rate returned to 65 beats / min. Conclusion The rapid clinical application of amiodarone in patients with coronary heart disease with tachyarrhythmia is significant. It can relieve the clinical symptoms quickly with less adverse reactions and high safety. It is worth to be popularized clinically.