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新型隐球菌脑膜炎是一种较少见的亚急性或慢性感染的疾病,但近年来有增加的趋势,我院1985年收治二例,均在脑脊液(CSF)中找到典型的新型隐球菌而确诊.据报告本病CSF的免疫球蛋白(Ig)甚少,我们用琼脂扩散法测定Ig,发现IgM显著增高,例1IgG16.0mg/dl,IgA 0mg/dl, IgM8.1mg/dl;例21gG27.3mg/dl,lgA 0 mg/dl,IgM26.8mg/dl。讨论测定CSF中Ig对中枢神经系统疾患的诊断具有重要意义,正常人CSF中Ig含量极少,IgG为3.68±2.14 mg/dl,IgA1.55±1.27mg/dl,IgM缺如。当中枢神经系
Cryptococcus neoformans meningitis is a rare sub-acute or chronic infection of the disease, but in recent years there is an increasing trend in our hospital in 1985 were treated in two cases, all found in the cerebrospinal fluid (CSF) typical Cryptococcus neoformans and Confirmed .It is reported that the disease CSF immunoglobulin (Ig) is very small, we use the agar diffusion method for the determination of Ig, IgM was significantly higher, Example 1IgG16.0mg / dl, IgA0mg / dl, IgM8.1mg / dl; Example 21gG27 .3 mg / dl, lgA 0 mg / dl, IgM 26.8 mg / dl. DISCUSSION Determining Ig in CSF is of great importance in the diagnosis of central nervous system disorders. Ig levels in normal CSF are very low, with IgG of 3.68 ± 2.14 mg / dl, IgA 1.55 ± 1.27 mg / dl, and absence of IgM. When the central nervous system