论文部分内容阅读
作者检测了67例冠心病患者和127例正常人的血小板粘附性(pAd)和血小板集聚性(pAg)。急性心肌梗塞(AMI)患者pAd明显升高(P<0.01),心绞痛患者次之(P<0.05)。除AMI症状发作3天内检测pAg外,在冠心病各亚组中血小板最大聚集率(%max)明显高于正常对照组(P<0.01),以不稳定型心绞痛者为最高。AMI症状发作3天内检测者,%max较低(P<0.05)。3例冠心病患者的血小扳超微结构显示血小板内颗粒较正常音减少。本文结果提示,冠心病患者血小板功能异常以及血小板形态发生改变。
The authors tested platelet adhesion (pAd) and platelet aggregation (pAg) in 67 patients with coronary heart disease and 127 healthy individuals. Patients with acute myocardial infarction (AMI) had significantly higher pAd (P <0.01) and angina pectoris (P <0.05). In addition to the detection of pAg within 3 days after onset of AMI, the maximum platelet aggregation rate (% max) in each subgroup of coronary heart disease was significantly higher than that of the normal control group (P <0.01), with unstable angina pectoris being the highest. AMI symptoms within 3 days of onset of the test,% max lower (P <0.05). The ultrastructure of platelets in 3 patients with coronary heart disease showed that intraplatelet particles were less than normal. The results suggest that patients with coronary heart disease platelet dysfunction and changes in platelet morphology.