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目的 :采用炭末测定法观察中药荔枝草对小鼠小肠运动的影响。方法 :将70只实验小鼠随机分为阳性对照组(枳壳水煎剂组)、荔枝草水煎剂组(10、15、20、25、30 g/kg)和生理盐水组,灌胃3 d(均为0.2 mL/10 g)后采用炭末测定法对小鼠的小肠运动情况进行观察分析。结果 :荔枝草水煎剂组对小鼠小肠推进率比生理盐水组的推进率明显提高(P<0.05);荔枝草水煎剂浓度在10~20 g/kg范围内对小肠的推进率逐渐增强,在20~30 g/kg范围内其效果逐渐减弱。结论 :荔枝草水煎剂有一定的促小肠运动作用,并呈现一定的量效关系,其中以20 g/kg浓度的荔枝草水煎剂对小鼠小肠的推动作用最为显著。
OBJECTIVE: To observe the effect of Chinese herbal medicine Lychee grass on intestinal motility in mice by carbon powder assay. Methods: 70 experimental mice were randomly divided into positive control group (Fructus Aurantii decoction group), lychee decoction group (10,15,20,25,30 g / kg) and saline group, 3 d (both 0.2 mL / 10 g) after the use of carbon determination of small intestine movement in mice were analyzed. Results: The propulsion rate of small intestine in mice was significantly higher than that in saline group (P <0.05). The propulsion rate of lychee to decoction of small intestine was gradually decreased from 10 g / kg to 20 g / kg Enhanced, its effect gradually weakened in the range of 20 ~ 30 g / kg. CONCLUSION: The watermelon decoction has some promoting intestinal motility and shows a certain dose-effect relationship. Among them, the promotion of small intestine is the most significant in the group of 20 g / kg thallus decoction.