艰难梭菌感染与外周血白细胞增多的关系

• 作 者: 莫凌
• 出 处: 国外医学(微生物学分册)
• 发表日期: 2003年03期
• 关键词: 艰难梭菌感染 白细胞增多 假膜性肠炎 白细胞计数 黏膜感染 前瞻性观察 血液系统疾病 组织炎症 Houston 艰难梭菌毒素

经验提示艰难梭菌感染在外周血白细胞增多的病人,特别是白细胞计数≥30×10~9/L的群体中占有很大比例。这种杆菌是黏膜感染的常见病原,可引起腹泻、发热和假膜性肠炎。为此,本文作者对三级医院白细胞计数>15×10~9/L的住院和门诊病人进行了一项前瞻性观察研究,以明确与外周血白细胞增多相关的原因,特别是艰难梭菌感染在其中的地位。

Experience has shown that C. difficile infection accounts for a large proportion of patients with peripheral leukocytosis, especially those with a white blood cell count> 30x10-9 / L. This bacillus is a common cause of mucosal infections that can cause diarrhea, fever and pseudomembranous colitis. To this end, the authors conducted a prospective observational study of inpatients and outpatients with leukocyte counts> 15 × 10 ~ 9 / L in tertiary hospitals to clarify the causes associated with peripheral leukocytosis, particularly C. difficile infection In which position.