论文部分内容阅读
目的探讨动态脑电图(AEEG)在发作间期儿童癫痫诊疗中的价值。方法 采用康泰CMS4000动态脑电图仪于发作间期24h监测分析98例癫痫儿童并对其AEEG异常率相关因素进行比较分析。结果 AEEG监测异常者84例(85.7%)。84例中有痫样放电者59例(60.2%)[其中48例(49.0%)兼有非特异性异常];仅有非特异性异常者25例(25.5%)。AEEG痫样放电率在不同的发作频率(无发作、<1次/月、≥1次/月)组间比较存在显著差异,发作越频繁,痫样放电阳性率越高(P<0.01)。59例痫样放电者中,出现在清醒期4例(6.8%),出现在睡眠期者27例(45.8%),清醒及睡眠期均出现28例(47.5%),睡眠期与清醒+睡眠期痫样放电检出率高于清醒期(P<0.01)。非特异性异常者73例中,出现在清醒期者5例(6.8%),出现在睡眠期者23例(31.5%),清醒及睡眠中均出现者45例(61.6%),睡眠期与清醒+睡眠期非特异性异常检出率高于清醒期(P<0.01)。治疗后复查的癫痫儿童较新诊断的癫痫儿童痫样放电率明显降低(40.7%vs59.3%,P<0.01)。结论 AEEG能在自然状态下长时间记录患儿清醒、睡眠各种状态的脑电活动,可提高发作间期癫痫儿童痫样放电及非特异性异常检出率,有助于儿童癫痫的临床诊断、疗效评估。
Objective To investigate the value of dynamic electroencephalogram (AEEG) in diagnosis and treatment of childhood epilepsy during interictal period. Methods Fortine CMS4000 dynamic electroencephalograph was used to detect and analyze 98 cases of epilepsy children during the interictal period of 24 hours. The related factors of AEEG abnormality rate were compared and analyzed. Results AEEG monitoring abnormalities in 84 cases (85.7%). Among the 84 patients, 59 (60.2%) had epileptiform discharges [48 (49.0%) had both nonspecific abnormalities]; only 25 (25.5%) had nonspecific abnormalities. There were significant differences in the epileptiform discharge rate of AEEG among different seizure frequencies (no seizure, <1 time / month, ≥ 1 time / month). The more frequent the seizures, the higher the positive rate of epileptic discharge (P <0.01). Among the 59 cases of epileptic discharges, there were 4 cases (6.8%) in awake stage, 27 cases (45.8%) in sleep stage, 28 cases (47.5%) in awake and sleep stage, sleep and awake The detection rate of epileptiform discharge was higher than awake (P <0.01). Among the 73 patients with nonspecific abnormalities, there were 5 cases (6.8%) in the awake period, 23 cases (31.5%) in the sleep stage, 45 cases (61.6%) in the awake and sleep stage, the sleep stage and the awake + The detection rate of nonspecific abnormalities during sleep was higher than that during awake (P <0.01). The epileptiform discharge rate in children with epilepsy after the treatment was significantly lower than those in the newly diagnosed epilepsy children (40.7% vs59.3%, P <0.01). Conclusions AEEG can record the brain electrical activity of awake and sleep in a long time under natural conditions and can improve the detection rate of epileptiform discharge and nonspecific abnormality in children with interictal epilepsy. It is helpful for clinical diagnosis of epilepsy in children, Efficacy evaluation.