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目的:比较分析不同照射时间与间歇时间的蓝光照射对新生儿黄疸的疗效。方法:对2012年1月—5月富阳市妇幼保健院新生儿室收治的新生儿黄疸患儿,随机分成三组,病人每天总光疗时间相同而间歇期不同进行分次间歇蓝光治疗,3天一个疗程。光疗前后进行血生化分析测定血清总胆红素值,比较光疗后血清总胆红素值与下降值,评估疗效。结果:光疗后血清总胆红素值均下降,光疗后血清总胆红素值与下降值比较A组与B组差异具有统计学意义,其他组间差异无统计学意义。结论:在分次间歇照射研究中,对患儿每次接受蓝光照射4h后停止照射4h为一个照射周期;对照组患儿接受8h蓝光照射后停止照射16h,疗效相当。根据本研究结果不建议对间歇照射的每次时间4h与间歇时间4h的基础上再缩短,以免影响光疗效果。
OBJECTIVE: To compare and analyze the curative effect of neonatal jaundice by blue light irradiation with different irradiation time and intermittent time. Methods: Neonatal jaundice children admitted to the Neonatology Center of Fuyang Maternal and Child Health Hospital from January to May in 2012 were divided into three groups at random. The patients had the same total phototherapy time but intermittent periods with intermittent intermittent blue light therapy for three days A treatment. Blood biochemical analysis before and after phototherapy to determine serum total bilirubin values, serum photochemical total bilirubin value and the decline compared to assess the efficacy. Results: The serum total bilirubin value decreased after phototherapy. The total serum bilirubin value and descended value after phototherapy were significantly different between group A and group B. There was no significant difference among the other groups. Conclusion: In fractional intermittent irradiation study, children were irradiated with blue light for 4 hours and then stopped for 4 hours for one irradiation period. Children in control group received irradiation for 8 hours and then stopped for 16 hours. According to the results of this study is not recommended for intermittent irradiation every time 4h and intermittent time 4h basis and then shorten, so as not to affect the phototherapy effect.