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目的观察脉压与冠状动脉病变严重程度的相关性。方法 231例经冠状动脉造影确诊的冠心病患者,男165例,女66例,年龄33～72岁,平均(51.13±11.62)岁。行24h无创动态血压监测,按动态脉压分为三组:脉压<40mmHg组(59例)、40～60 mmHg组(107)、>60 mmHg组(65)。冠状动脉病变严重程度用冠状动脉病变支数来评价。结果合并高血压的患者冠状动脉双支(43.2%比9.1%)及三支(27.6%比11.2%)血管病变的患病率显著高于非高血压组;三组不同脉压的患者相比,脉压<40mmHg组、40～60 mmHg组、>60 mmHg组的患者冠状动脉三支血管病变的患病率分别为8.7%、23.5%、42.7%。结论脉压是方便的反映大动脉弹性的参数,与冠状动脉病变严重程度密切相关,是全身心血管病的一个危险信号,可指导早期干预。
Objective To observe the correlation between pulse pressure and the severity of coronary artery disease. Methods Totally 231 patients with coronary heart disease confirmed by coronary angiography were 165 males and 66 females aged 33-72 years with an average of (51.13 ± 11.62) years. Noninvasive ambulatory blood pressure monitoring was performed 24 hrs and divided into three groups according to dynamic pulse pressure: pulse pressure <40 mmHg group (59 cases), 40-60 mmHg group (107) and> 60 mmHg group (65). The severity of coronary artery disease was assessed by the number of coronary lesions. Results The prevalence of coronary lesions in both hypertensive patients (43.2% vs 9.1%) and three vessels (27.6% vs 11.2%) was significantly higher than that in non-hypertensive patients. Compared with patients with different pulse pressures The prevalence rates of coronary artery disease were 8.7%, 23.5% and 42.7% in patients with pulse pressure <40mmHg, 40 ~ 60mmHg and> 60mmHg respectively. Conclusion Pulse pressure is a convenient parameter to reflect the elasticity of aorta, which is closely related to the severity of coronary artery disease. It is a dangerous signal of systemic cardiovascular disease and can guide early intervention.