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应用图像分析技术对１０３例子宫内膜癌癌细胞中ＡｇＮＯＲ进行了定量研究。结果表明，低分化、肌层浸润＞１／２者的癌细胞核面积、每核ＡｇＮＯＲ颗粒总面积、颗粒数及颗粒平均面积明显大于高分化及无肌层浸润者。Ⅱ、Ⅳ期、复发、死亡患者的癌细胞的核面积及ＡｇＮＯＲ颗粒平均面积较Ⅰ期、无复发、存活者明显增高。ＡｇＮＯＲ的颗粒平均面积多在１．２０μｍ×１．２０μｍ以上，并且ＡｇＮＯＲ颗粒分布多呈聚集型；而预后较好的患者，ＡｇＮＯＲ颗粒平均面积多在亚．１５μｍ×１．１５μｍ左右，颗粒多呈弥散分布。结果提示，细胞内ＡｇＮＯＲ的含量与子宫内膜癌的生物学行为及预后有关，图像分析进行ＡｇＮＯＲ的定量研究较传统的光镜下计数ＡｇＮＯＲ颗粒数目更为客观、准确。
103 cases of endometrial cancer cells AgNOR quantitative analysis using image analysis technology. The results showed that the total area, number of particles and the average area of AgNOR particles per core were significantly larger than those of the well-differentiated and myometrial-infiltrated ones. In stage Ⅱ and Ⅳ, the area of cancer cells and the average area of AgNOR particles in patients with recurrence and death were significantly higher than those in stage Ⅰ without recurrence. The average area of AgNOR particles was more than 1.20μm × 1.20μm, and AgNOR particles were mostly aggregated. In the patients with better prognosis, the average area of AgNOR particles was mostly in Asia. 15μm × 1.15μm or so, mostly dispersed particles. The results suggest that the content of intracellular AgNOR is related to the biological behavior and prognosis of endometrial carcinoma. Quantitative analysis of AgNOR in image analysis is more objective and accurate than counting the number of AgNOR particles under the light microscope.