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人的ABO血型终生不变众所周知,然在个别癌症及白血病患者,血型偶可发生变异,国内外已有数列报导。我院于1982年收治直肠癌引起血型变异一例,报告如下。患者:女,61岁,汉族,沈阳市人,因便血及排便困难消瘦3-4个月,于1982年11月8日入院。入院全身检查大致正常。肛诊膝肘位见肛缘内2cm于7点至2点处菜花状肿物。有触痛,指诊出血。肝功能心电图、血象检查正常。诊断“直肠肛管癌”同月18日行直肠根治术人造肛门。病理诊断“直肠腺癌”。术中,输血查血型A型,交叉凝集试验,主次侧均无凝集。(此患十多年前因献血在沈医查为“A”型)。术中输A型血910ml,无任何反应。病人一般状况好。于1983年1月4日出院。术后两个月为化疗再入院,因贫血输“A”型血,交叉配血,次侧出现凝集反应。复查血为“AB”型。因与前不符未敢输血,化疗后出院。1983年7月8日再次化疗。因贫血,化疗前给血,
It is well known that human ABO blood type lasts for a long time. However, in some patients with cancer and leukemia, the blood type can mutate occasionally. There are several reports at home and abroad. Our hospital in 1982 admitted to a case of rectal cancer caused by blood group variation, the report is as follows. Patients: Female, female, 61 years old, Han nationality, Shenyang city people, because of hematochezia and defecation difficulty wasting 3-4 months, on November 8, 1982 admitted. Admission general examination was normal. Anal see elbow knee anal margin 2cm at 7 o’clock to 2 o’clock cauliflower-like mass. Have tenderness, referral bleeding. Liver function electrocardiogram, blood test was normal. Diagnosis of “rectal cancer” On the same month on the 18th rectal radical artificial anus. Pathological diagnosis of “rectal adenocarcinoma.” Intraoperative blood transfusion type A blood test, cross-coagulation test, primary and secondary no agglutination. (This affected more than a decade ago because of blood donation in the medical examination for the “A” type). Blood transfusion type A 910ml, no reaction. The general condition of the patient is good. Was discharged on January 4, 1983. Chemotherapy after two months of re-admission, due to anemia lose “A” type blood, cross-matching blood, secondary agglutination. Review the blood for the “AB” type. Because of incompatible with the former did not dare transfusion, chemotherapy after discharge. July 8, 1983 chemotherapy again. Because of anemia, blood before chemotherapy,