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在20世纪60年代中期,非选择性β阻滞剂心得安已被用于治疗心绞痛和高血压。从此,新的β阻滞剂不断出现,临床应用也日益广泛。但其作用可以影响病人的日常生活或健康。β阻滞剂的副作用按药理学分为可预料和不可预料两部分,前者表现为心动过缓、支气管痉挛、肌无力、肢冷等,是药物的正常药效结果,与药物剂量有关;后者表现为恶心、肠道功能失调等肠胃道症状、皮肤反应、性功能障碍和中枢神经系统(CNS)有关的情绪失调,这些副作用与药物剂量无关。本文对β阻滞剂治疗引起的CNS副作用
In the mid-1960s, non-selective beta blocker propranolol had been used to treat angina pectoris and hypertension. Since then, new beta blockers continue to emerge, clinical application is also increasingly widespread. But its role can affect the patient’s daily life or health. Beta blockers side effects according to pharmacology can be divided into two parts can be expected and unpredictable, the former showed bradycardia, bronchospasm, muscle weakness, cold limbs, is the drug’s normal efficacy results, and the dose of the drug; the latter Gastrointestinal symptoms such as nausea, bowel dysfunction, cutaneous reactions, sexual dysfunction and central nervous system (CNS) -related mood disorders are not related to drug dose. This article treats CNS side effects caused by beta blockers