论文部分内容阅读
目的对金沙槭的化学成分进行系统研究。方法采用硅胶柱色谱、Sephadex LH-20柱色谱、ODS柱色谱、HPLC等手段对金沙槭的乙醇提取物进行分离纯化,并通过化合物理化性质与波谱特征鉴定其结构。结果分离鉴定13个化合物,分别为:槲皮素(quercetin,1)、槲皮素3-O-α-L-阿拉伯糖苷(quercetin 3-O-α-L-arabinoside,2)、槲皮素3-O-α-L-鼠李糖苷(quercetin 3-O-α-L-rhamnoside,3)、槲皮素3-O-β-D-半乳糖苷(quercetin 3-O-β-D-galactopyranoside,4)、山奈酚(kaempferol,5)、山柰酚3-O-α-L-鼠李糖苷(Kaempferol 3-O-α-L-rhamnoside,6)、山奈酚3-O-β-D-葡萄糖苷(kaempferol 3-O-β-D-glucopyranoside,7)、山奈酚3-O-β-D-半乳糖苷(kaempferol 3-O-β-D-galactopyranoside,8)、山奈酚3-O-α-L-阿拉伯糖苷(kaempferol 3-O-α-L-arabinoside,9)、杨梅酮(myricetin,10)、儿茶素(catechins,11)、金线吊乌龟二酮碱A(cepharadione A,12)、巴马汀(palmatine,13)。结论化合物9、12、13为首次从槭属中分离得到。化合物1-13均为首次从该植物中分离得到。
Aim To systematically study the chemical constituents of Acer davidiana. Methods The silica gel column chromatography, Sephadex LH-20 column chromatography, ODS column chromatography and HPLC were used to separate and purify the ethanolic extract of Acer davidiana. The structures of the compounds were identified by physicochemical and spectroscopic methods. Results Thirteen compounds were isolated and identified as quercetin (1), quercetin 3-O-α-L-arabinoside (2), quercetin 3-O-α-L-rhamnoside (3), quercetin 3-O-β-D- galactopyranoside (4), kaempferol (5), Kaempferol 3-O-α-L-rhamnoside (6) Kaempferol 3-O-β-D-glucopyranoside (7), kaempferol 3-O-β-D-galactopyranoside (8) O-α-L-arabinoside (9), myricetin (10), catechins (11) cepharadione A, 12), palmatine (13). Conclusion Compounds 9, 12 and 13 were isolated from Acer palmatum for the first time. Compounds 1-13 were isolated from this plant for the first time.