Systematic review of the old and new concepts in the epithelial-mesenchymal transition of colorectal

• 作 者: Simona Gurzu Camelia Silveanu
• 机 构: DepartmentofPathology,DepartmentofSurgery,DepartmentsofGeneticsandBiochemistry
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2016年30期
• 关键词: ANGIOGENESIS Colorectal cancer BUDDING Epithelial-mesenchymal transition CHEMORE
• 基金项目: University of Medicine and Pharmacy of TirguMures,Romania,Team Research Projects Frame:UMFTGMPO-CC-02-F01,No.19/2014

Epithelial-to-mesenchymal transition(EMT) is defined as the transformation of an epithelial cell into a spindle cell with the loss of membrane E-cadherin expression and the gain of mesenchymal markers positivity. In the field of colorectal cancer(CRC), fi