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对４４例晚期妇科恶性肿瘤患者施行选择性动脉管插管化疗８３例次．其中行微球栓塞治疗１５人，为２８例次。４４例患者均为进展期或复发性晚期妇科恶性肿瘤，临床分期Ⅱ期３９例．Ⅳ期５例。各类卵巢癌３９例，宫颈癌４例，阴道癌１例，随访率１００％。显示完全有效（ＣＲ）９例，部分有效（ＰＲ）１７例，轻微有效（ＭＲ）１７例，无效（ＮＣ）且例，近期有效率（ＣＲ＋ＰＲ）达５９．１％。抗肿瘤效果肯定，副反应如较严重胃肠道反应占２３．２％，明显骨髓抑制占４．８％，肝功能损害占２．４％，高热占３．６％，严重腹泻占１．２％，深部血肿占１．２％，穿刺部位出血占１．２％，臀痛占４３％，下肢麻木占１４％，神经损害致下肢瘫痪占１．２％。为减少和避免严重并发症发生，在行选择性动脉插管灌注化疗药物前，以明胶海绵碎块先行臀上动脉栓塞，阻止药物分流，为减少神经损伤，插管时应避开髂内动脉后支。
Forty-four patients with advanced gynecological malignant tumors underwent selective arterial catheterization of 83 cases. Among them, 15 patients underwent microsphere embolization for 28 cases. Forty - four patients were all advanced or recurrent advanced gynecological malignancies, with 39 cases in stage Ⅱ. Ⅳ period in 5 cases. 39 cases of various types of ovarian cancer, cervical cancer in 4 cases, 1 case of vaginal cancer, follow-up rate of 100%. Nine patients were fully effective (CR), 17 were partially effective (PR), 17 were slightly effective (MR), 59 were NC (effective) and the rate of recent response (CR + PR) was 59.1%. Affirmative anti-tumor effect, side effects such as more serious gastrointestinal reactions accounted for 23.2%, significantly bone marrow suppression accounted for 4.8%, 2.4% of liver damage, high fever accounted for 3.6%, severe diarrhea accounted for 1. 2%, deep hematoma accounted for 1.2%, puncture site bleeding accounted for 1.2%, hip pain 43%, lower limb numbness 14%, nerve damage caused by lower limb paralysis 1.2%. In order to reduce and avoid the occurrence of serious complications, before selective arterial intubation chemotherapeutic drugs, gelatin sponge fragments first embolization of the upper gluteal artery to prevent drug diversion, in order to reduce nerve damage, intubation should be avoided when the internal iliac artery After the branch.