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目的:探讨中成药与西药联合应用的不良反应。方法:以该院2014年7月至2015年7月122例发生中成药与西药联合应用不良反应的患者为研究对象,对其临床资料进行回顾性分析,研究导致不良反应的原因。结果:122例患者中,毒性反应、过敏反应、二重感染和特异性反应这四类药物不良反应的发生率分别为17.21%、12.30%、33.60%和36.89%。122例发生药物不良反应的患者中,21例患者(17.21%)由用药途径不当引起,91例患者(74.59%)由药物配伍不当引起,其他原因引起的患者有10例(8.20%)。结论:临床用药时,应对西药和中成药的使用禁忌进行了解,达到中成药和西药联合使用的真正目的,避免联合用药发生不良反应。
Objective: To explore the adverse reactions of the combination of proprietary Chinese medicines and western medicine. Methods: From July 2014 to July 2015 in our hospital, 122 patients with combined Chinese patent medicine and western medicine were enrolled in this study. The clinical data were retrospectively analyzed to study the causes of adverse reactions. Results: Among 122 patients, the incidences of adverse reactions such as toxic reaction, allergic reaction, double infection and specific reaction were 17.21%, 12.30%, 33.60% and 36.89% respectively. Of the 122 patients who developed adverse drug reactions, 21 patients (17.21%) were caused by improper administration of drugs. 91 patients (74.59%) were caused by incompatible drugs and 10 patients (8.20%) caused by other reasons. Conclusion: Clinical medication, should be contraindicated in the use of western medicine and proprietary Chinese medicine to understand, to achieve the real purpose of the joint use of proprietary Chinese medicines and Western medicine to avoid adverse reactions combined with medication.