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长期大量应用甲种维生素所引起的慢性甲素遇多症(过敏,食欲不振,毛发脱落,皮肤改变及对称为肢体肿胀等)已为人所共知,惟短期大量甲素在乳儿所引起的“急性甲素过多症”尚少有报告。1951年Marie-See报告了4例由大量甲素(一日内曾服用35万单位)所引起的脑积水症,其后并经试验所证明,1954年慕尼黑大学儿科Ehrengut氏又报告一例,
Long-term large-scale application of vitamin A caused by a chronic multiple disease (allergies, loss of appetite, hair loss, skin changes and symmetrical swelling of the limbs, etc.) has been well known, but a large number of short- “A case of acute hyperlipidemia” is still rare. Marie-See reported in 1951 four cases of hydrocephalus caused by a large quantity of a-triazine, which took 350,000 units in a day. Afterwards, it was proved through experiments that one case was reported again by Ehrengut, a pediatrician at Munich University in 1954,