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为了解HAV/HBV双重感染的发生情况,作者检测了121例慢性乙型肝炎患者血清抗HAV-IgM,其中经类风湿因子免疫胶乳(RFIL)处理后抗HAV-IgM仍阳性的7例,未经处理的12例阳性,有5例为假阳性,占41.7％(5/12)。用RFIL能消除因血清中RF所致的抗HAV-IgM假阳性反应,不出现假阴性结果。认为RFIL中和反应是一种简单,经济而有效的排除RF干扰的方法。本组慢性乙型肝炎患者重叠感染甲肝病毒7例,占5.8％,均为慢性活动性肝炎。
To understand the occurrence of HAV / HBV infection, the authors tested serum anti-HAV-IgM in 121 patients with chronic hepatitis B, of whom 7 were still positive for anti-HAV-IgM after treatment with rheumatoid factor-immunoreactive latex (RFIL) The treated 12 cases were positive, 5 cases were false positive, accounting for 41.7% (5/12). RFIL can be used to eliminate anti-HAV-IgM false-positive reaction due to RF in serum, and no false-negative result occurs. RFIL neutralization reaction is considered a simple, economical and effective way to eliminate RF interference. This group of patients with chronic hepatitis B infection of hepatitis virus overlap in 7 cases, accounting for 5.8%, are chronic active hepatitis.