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选取我院2012年9月~2014年9月所收治的100例肝硬化失代偿期并上消化道出血患者,将其作为本次的研究对象,并分成对照组和观察组各50例,对照组患者给予垂体后叶素进行治疗,观察组患者在对照组患者的基础上联合醋酸奥曲肽,记录患者止血时间,观察患者的治疗效果,同时对患者在治疗期间所出现的不良反应做好相应的记录,并比较两组。结果经过治疗后,两组患者的病情均得到不同程度改善,观察组患者止血时间5.94±1.46h,短于对照组患者止血时间10.27±2.06h,其中,观察组总有效率为94%,对照组总有效率为78%,此外,在不良反应方面,观察组中有1例患者出现耳鸣,1例患者出现腹泻,不良反应发生率为4%;对照组中有3例患者出现眩晕,2例患者出现恶心,3例患者出现腹痛,不良反应发生率为16%,比较两组患者的治疗效果差异明显(P<0.05),具有统计学意义。在肝硬化失代偿期并上消化道出血患者的治疗过程中,患者在常规治疗的基础上联合醋酸奥曲肽能够缩短止血时间,降低患者的不良反应,显著提高治疗效果,在临床上具有极为重要的意义,值得今后推广和应用。
100 patients with decompensated cirrhosis and upper gastrointestinal hemorrhage admitted in our hospital from September 2012 to September 2014 were selected as the study subjects and divided into control group and observation group of 50 cases each, Patients in the control group were treated with pituitrin. Patients in the observation group were treated with octreotide acetate on the basis of the control group. The bleeding time of the patients was recorded and the therapeutic effect was observed. At the same time, the adverse reaction occurred during the treatment Record, and compare the two groups. Results After treatment, the two groups of patients have been improved to varying degrees, the observation group patients to stop bleeding time 5.94 ± 1.46h, shorter than the control group bleeding time 10.27 ± 2.06h, of which the observation group the total effective rate 94%, control In addition, in adverse reactions, tinnitus occurred in 1 patient in the observation group, diarrhea occurred in 1 patient and the incidence of adverse reactions was 4%. In the control group, 3 patients developed dizziness, 2 Nausea occurred in the patients, abdominal pain occurred in 3 patients, and the incidence of adverse reactions was 16%. There was significant difference (P <0.05) in the treatment effect between the two groups, with statistical significance. In patients with decompensated liver cirrhosis and upper gastrointestinal bleeding in the course of treatment, the patients on the basis of conventional treatment with octreotide acetate can shorten the time to stop bleeding, reduce adverse reactions in patients with significantly improved treatment, clinically important The significance of the future worth promoting and application.