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目的:通过参与脓毒症重症肺炎患儿抗菌药物治疗过程,探讨儿科临床药师在抗菌药物合理使用中如何发挥作用。方法:临床药师对1例脓毒症重症肺炎患儿进行抗菌药物治疗监护,在患儿入院初期根据患儿情况建议临床不采用哌拉西林/他唑巴坦联用万古霉素方案,治疗中建议调整哌拉西林/他唑巴坦治疗剂量,并对抗真菌药物如制霉菌素在儿童特殊人群的使用等进行药学监护。结果:临床药师对抗菌药物治疗情况判断正确,处理得当,协助临床医师正确合理地使用了抗菌药物。结论:临床药师参与脓毒症重症肺炎患儿临床抗菌药物治疗,进行药学监护,可以提高抗菌药物治疗效果,减少不良反应发生。
OBJECTIVE: To explore the role of pediatric clinical pharmacists in the rational use of antimicrobial agents by participating in the course of antimicrobial treatment in children with severe pneumonia of sepsis. Methods: Clinical pharmacists conducted an anti-bacterial drug treatment on 1 patient with sepsis and severe pneumonia. In the early stage of admission, according to the situation of children, it is recommended that no piperacillin / tazobactam combined with vancomycin should be used in the treatment. Proposed to adjust the piperacillin / tazobactam treatment dose, and antifungal agents such as nystatin in children with special populations such as the use of pharmacy care. Results: The clinical pharmacists correctly diagnosed the antibacterials and treated them properly to help the clinicians use the antibacterials correctly and reasonably. Conclusion: Clinical pharmacists are involved in the clinical antibacterial treatment in children with sepsis and severe pneumonia. Pharmacological monitoring can improve the therapeutic effect of antimicrobial drugs and reduce adverse reactions.