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为了研究肝炎后肝硬化与肠道菌群间的关系，对４６名肝炎后肝硬化患者和５２名健康对照者进行了对比研究。方法为取０．５克新鲜粪便，用稀释液按１０倍稀释法将粪便稀释至１０－８，然后用滴注法接种于选择性培养基。选择肠道菌群中具代表性的需氧菌和厌氧菌共１０种。结果示：（１）实验组的肠杆菌、葡萄球菌、酵母菌、拟杆菌和双歧杆菌量明显低于对照组（Ｐ＜０．０１）。（２）伴腹泻者真杆菌减少，梭菌增加（Ｐ＜０．０５）。结果表明，肝硬化患者均有不同程度的肠菌群失调，而失调的程度往往与肝功能损害程度有关。
In order to study the relationship between posthepatitic cirrhosis and intestinal flora, 46 hepatitis cirrhosis patients and 52 healthy controls were compared. Method is to take 0.5 grams of fresh manure, diluted with a dilution of 10-fold dilution of stool diluted to 10-8, and then instilled in selective medium with the infusion method. Select the intestinal flora representative of aerobic and anaerobic bacteria a total of 10 species. The results showed: (1) The experimental group of Enterobacteriaceae, Staphylococcus, yeast, Bacteroides and Bifidobacterium was significantly lower than the control group (P <0.01). (2) Bacillus with diarrhea reduced, Clostridium increased (P <0.05). The results showed that patients with cirrhosis have different degrees of intestinal flora, and the degree of imbalance is often related to the degree of liver damage.