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Objective:To investigate the high risk factors and methods of prevention and treatment of o-varian hyperstimulation syndrome (OHSS) in assisted reproductive techniques (ART). Methods: Clinical data of 93 cycles of OHSS patients after IVF-ET treatment from Apr. 1989 to Oct. 2002 were analyzed retrospectively. Results:(1) A large number of follicles stimulated, luteal phase support with HCG and pregnancy were high risk factors to induce OHSS. (2) Longer disease process, more severe symptoms and more albumins used for treatment of OHSS were commonoy observed in pregnant patients with OHSS compared with non-pregnant ones. (3) Vena dropping human serum albumin is one of the most successful treatment as plasma expanders through restoration of colloid osmotic pressure; paracentesis is necessary for critical OHSS patients with severe ascites and hydrothorax; (4) Occasionally therapeutic abortion of an early gestation may be an only way for lifesaving when all other methods have failed. Conclusions: OHSS is a serious complication of controlled ovarian hyperstimulation. Proper prevention and treatment of OHSS are important for patient safety in ART.
Objective: To investigate the high risk factors and methods of prevention and treatment of o-varian hyperstimulation syndrome (OHSS) in assisted reproductive techniques (ART). Methods: Clinical data of 93 cycles of OHSS patients after IVF-ET treatment from Apr. 1989 To: Oct. 2002 were analyzed retrospectively. Results: (1) A large number of follicles stimulated, luteal phase support with HCG and pregnancy were high risk factors to induce OHSS. (2) Longer disease process, more severe symptoms and more albumins used for treatment of OHSS were commonoy observed in pregnant patients with OHSS compared with non-pregnant ones. (3) Vena dropping human serum albumin is one of the most successful treatment as plasma expanders through restoration of colloid osmotic pressure; paracentesis is necessary for critical OHSS patients with severe ascites and hydrothorax; (4) Occasionally therapeutic abortion of an early gestation may be only only for lifesaving when all other methods have failed. Conclus ions: OHSS is a serious complication of controlled ovarian hyperstimulation. Proper prevention and treatment of OHSS are important for patient safety in ART.