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目的探讨兰索拉唑联用吗丁啉治疗胃食管反流病的临床疗效。方法 198例胃食管反流病患者随机分为观察组与对照组,每组99例,对照组给予兰索拉唑治疗,观察组在对照组基础上加用吗丁啉治疗,对治疗后两组临床症状改善情况与电子胃镜复查黏膜修复情况进行比较分析。结果观察组临床症状改善率为92.93%,对照组临床症状改善率为74.75%,两组比较差异有统计学意义(P<0.05)。复查电子胃镜结果黏膜修复情况,观察组总有效率为91.92%,对照组总有效率为73.74%,两组比较差异有统计学意义(P<0.05)。结论兰索拉唑联用吗丁啉治疗胃食管反流病,效果显著。
Objective To investigate the clinical efficacy of lansoprazole combined with domperidone in the treatment of gastroesophageal reflux disease. Methods A total of 198 patients with gastroesophageal reflux disease were randomly divided into observation group and control group, 99 cases in each group. The control group was treated with lansoprazole. The observation group was treated with domperidone on the basis of the control group. Group clinical symptoms and electronic gastroscopic review mucosal repair comparative analysis. Results The improvement rate of clinical symptoms in the observation group was 92.93%, while that in the control group was 74.75%. There was significant difference between the two groups (P <0.05). Review of electronic endoscopy mucosal repair results, the observation group the total effective rate was 91.92%, the control group was 73.74%, the difference between the two groups was statistically significant (P <0.05). Conclusion Lansoprazole combined with domperidone in the treatment of gastroesophageal reflux disease, the effect is significant.