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目的观察参芎葡萄糖注射液治疗急性心梗冠脉介入术后患者,对其左室重塑的影响。方法选择急性心梗12h内行PCI的患者112例,随机分为观察组和对照组,观察组加用参芎葡萄糖注射液。结果治疗4周后,心脏超声LVESV、LVEDV较对照组降低,而LVEF则较对照组增高(P<0.05);在降低心梗并发症方面低于对照组(P<0.05)。结论参芎葡萄糖注射液能改善急性心梗后早期心室重塑及预后,是治疗急性心肌梗死有效而安全的药物。
Objective To observe the effect of Shenxiong and glucose injection on left ventricular remodeling after coronary intervention in patients with acute myocardial infarction. Methods 112 cases of acute myocardial infarction 12h PCI were randomly divided into observation group and control group, the observation group plus Shenxiong glucose injection. Results After 4 weeks of treatment, the LVESV and LVEDV in the echocardiography were lower than those in the control group, but LVEF was higher than that in the control group (P <0.05), but lower than that in the control group (P <0.05). Conclusion Shenxiong glucose injection can improve early ventricular remodeling and prognosis after acute myocardial infarction and is an effective and safe drug for the treatment of acute myocardial infarction.