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目的研究98例胃癌晚期患者进行姑息手术的临床疗效。方法选取2009年1月至2014年4月潍坊市肿瘤医院诊治的98例胃癌晚期患者的临床资料进行回顾性分析研究。按手术方式的不同将患者分为观察组与对照组,观察组52例,对照组46例。两组均给予化疗、营养支持等基础治疗,观察组实施姑息胃切除手术,对照组实施姑息非切除手术。并且术后进行定期随访。结果经姑息胃切除手术后,观察组不同时间点的生存率明显高于对照组,两组比较差异有统计学意义(P<0.01);观察组术后生活质量得到改善,与对照组相比差异有统计学意义(u=-2.2845,P=0.0223)。结论胃癌晚期患者行姑息手术能有效改善生活质量,延续生存期,尤其是姑息胃切除手术的疗效更好,条件允可者应选择姑息胃切除手术。
Objective To study the clinical efficacy of palliative surgery in 98 patients with advanced gastric cancer. Methods A retrospective analysis was performed on the clinical data of 98 patients with advanced gastric cancer diagnosed and treated in Weifang Cancer Hospital from January 2009 to April 2014. According to the different surgical methods, the patients were divided into observation group and control group, 52 cases in observation group and 46 cases in control group. Both groups were given basic treatment such as chemotherapy and nutrition support. The observation group was treated with palliative gastrectomy and the control group was treated with palliative resection. And regular follow-up after surgery. Results After palliative gastrectomy, the survival rate of the observation group at different time points was significantly higher than that of the control group, with significant difference between the two groups (P <0.01). The quality of life in the observation group improved compared with the control group The difference was statistically significant (u = -2.2845, P = 0.0223). Conclusions Palliative surgery in patients with advanced gastric cancer can effectively improve quality of life and prolong survival. In particular, palliative gastrectomy has a better curative effect. If conditions permit, palliative gastrectomy should be selected.