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【目的】通过前瞻性纵向监测贫血孕妇及其新生儿、婴儿的Hb,sTfR,分析孕妇贫血对婴儿6月龄时铁代谢的影响。【方法】随机抽取Hb<100 g/L的56例临产孕妇作为研究组,选取56例Hb>110 g/L的同孕周临产孕妇作为对照组,两组孕妇所生各56例新生儿、婴儿为子代研究组、子代对照组,婴儿于出生时、42 d、4个月、6个月进行定期体检,孕妇、新生儿、6月龄婴儿抽血检测Hb、sTfR。【结果】与对照组比较,贫血孕妇及其所生婴儿6月龄时的Hb、sTfR值差异有统计学意义(P<0.01),新生儿Hb、sTfR值差异无统计学意义(P>0.05)。贫血孕妇所生婴儿6月龄时IDA检出率为60.8%%,正常孕妇所生婴儿为21.6%,差异有统计学意义(P<0.01)。【结论】孕妇贫血是导致6月龄婴儿SID及IDA的主要危险因素。
【Objective】 The purpose of this study was to prospectively monitor the Hb, sTfR of anemic pregnant women and their newborns and infants, and to analyze the effect of anemia in pregnant women on the iron metabolism of infants at 6 months of age. 【Methods】 Fifty-six pregnant women with Hb <100 g / L were randomly selected as the study group. Fifty-six pregnant women of the same gestational age with Hb> 110 g / L as the control group were selected. 56 newborns, Babies were offspring group, offspring control group, infants at birth, 42 d, 4 months, 6 months regular physical examination, pregnant women, newborns, 6-month-old infants blood test Hb, sTfR. 【Results】 Compared with the control group, the Hb, sTfR values of anemia pregnant women and their infants at 6 months of age were significantly different (P <0.01), but there was no significant difference of Hb and sTfR between neonates and infants ). The detection rate of IDA in infants born to anemia at 6 months old was 60.8 %% and that in normal pregnant women was 21.6%, the difference was statistically significant (P <0.01). 【Conclusion】 Anemia in pregnant women is the main risk factor for SID and IDA in 6-month-old infants.