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冠状动脉慢性完全闭塞(CTO)病变的治疗包括药物保守治疗、介入治疗、外科治疗,其中药物治疗是基础,包括抗血小板药物、β-受体阻滞剂、硝酸酯类药物、他汀类药物、抗凝治疗等;进展最大的是介入治疗,开通CTO病变可以明显改善患者症状及预后,但对术者要求高,成功率低,术后再闭塞和再狭窄的发生率较高,被介入心脏病学家称为“最后一块前沿阵地”;外科治疗是早期治疗CTO病变的主要方法,经历了静脉桥、部分动脉桥及完全动脉桥3个阶段,本文就其治疗做一综述。
The treatment of chronic coronary artery full occlusion (CTO) lesion includes drug conservative treatment, interventional therapy and surgical treatment. Among them, drug therapy is the basis, including antiplatelet drugs, beta blockers, nitrates, statins, Anticoagulant therapy, etc .; the most progress is interventional therapy, open CTO lesions can significantly improve the patient’s symptoms and prognosis, but the surgeon demanding high success rate is low, the incidence of reocclusion and restenosis after high involvement of the heart The pathologist called the “last frontier”. Surgical treatment is the main method for early treatment of CTO lesions. It has undergone three stages of venous bridge, partial arterial bridge and complete arterial bridge. This article reviews its treatment.