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目的评价枸杞粉(滋补肝肾中药)对老年人体质状态的影响。方法用双盲、随机、安慰剂对照的临床试验设计,按年龄和性别进行分层。对健康老年人群(65～70岁,男女均衡)补充3个月枸杞粉前后中医证候的观察,给药组和对照组分别给予枸杞粉(每天13.7g)与安慰剂,每组75人。用中医诊断问卷,对补充枸杞3个月前后所有受试者的典型中医证候进行调查。结果和对照组相比,服用枸杞粉的老年人群的阴虚症状有明显改善,其中口干咽燥、心烦失眠和脉象3项指标均有显著性改善(P<0.01)。结论长期口服枸杞粉可使老龄人群的体质状况得到显著改善,这可能与枸杞中的抗氧化物质(玉米黄素)有关。
Objective To evaluate the effect of Chinese wolfberry powder (nourishing liver and kidney Chinese medicine) on the constitutional status of the elderly. Methods A double-blind, randomized, placebo-controlled clinical trial design stratified by age and sex. The observation of TCM syndromes before and after the wolfberry powder was supplemented for three months in healthy elderly population (65-70 years old, male-female balance) were given wolfberry powder (13.7g / day) and placebo in the medicine group and the control group, with 75 in each group. Using the TCM diagnostic questionnaire, we investigated the typical TCM syndromes of all subjects after 3 months of Chinese wolfberry supplementation. Results Compared with the control group, the symptoms of Yin deficiency were significantly improved in the elderly population taking wolfberry powder, with significant improvement of three indicators of xerostomia, insomnia and pulse (P <0.01). Conclusion Long-term oral administration of Chinese wolfberry powder can significantly improve the physical status of the elderly population, which may be related to the antioxidant substance in Chinese wolfberry (zeaxanthin).