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镍是一种潜在的变应原物质,它是引起变应性接触性皮炎的最常见病因之一。含镍的矫形外科植入物能引起过敏性皮炎。在全部患湿疹的病人中有5%是戴用装饰合金或职业性接触(如电镀工业)所致。各种基托金属都会发生腐蚀,腐蚀作用的产物使软组织产生炎症,在炎症的基础上激发过敏性皮炎。除了用不锈钢制作的植入物外,其它含镍或铬的植入物在体液内都会发生锈蚀,从而促使镍和铬的原子向周围组织内迁移。有很多种因素能影响镍过敏的发生,最重要的因素是机械刺激、皮肢浸渍、个体
Nickel is a potential allergenic substance that is one of the most common causes of allergic contact dermatitis. Nickel-containing orthopedic implants can cause atopic dermatitis. 5% of all patients with eczema are wearing decorative alloys or occupational exposure (such as the electroplating industry). A variety of Kevlar metal corrosion occurs, the product of the corrosive effect of soft tissue inflammation, based on the inflammatory activation of atopic dermatitis. In addition to implants made of stainless steel, other nickel- or chromium-containing implants rust in body fluids, encouraging the migration of nickel and chromium atoms into the surrounding tissue. There are many factors that can affect the occurrence of nickel allergy, the most important factor is the mechanical stimulation, skin limb immersion, individuals