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地索高诺酮系荷兰Organon药厂研究、开发的全合成孕激素避孕药,并有很强的抗雌激素活性,能抑制排卵及促性腺激素的分泌;复方片剂Marvelon每片含本品0.15mg与炔雌二醇0.03mg,用作口服避孕药。其特点是能有益地影响脂质代谢,使高密度脂蛋白中胆固醇升高,有助于减少心血管疾病发生的危险性,对糖代谢也无不良影响。这些都胜于其他口服甾体避孕药,例如炔诺酮、18-甲基炔诺酮等。它们具有降低高密度脂
Desopostone Department of the Netherlands Organon pharmaceutical research and development of fully synthetic progestin contraceptives, and a strong anti-estrogen activity, can inhibit ovulation and gonadotropin secretion; compound tablet Marvelon each containing this product 0.15 mg and ethinyl estradiol 0.03 mg for oral contraceptives. It is characterized by beneficial effects on lipid metabolism, elevated cholesterol in high-density lipoprotein, helps to reduce the risk of cardiovascular disease, and has no adverse effect on glucose metabolism. These are better than other oral steroid contraceptives, such as norethindrone, 18-norgestrel and so on. They have the benefit of reducing high-density lipids