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眼用溶液在大量生产上会发生许多问题,如毛混率的不稳定、杂質的掺入、工具材料对眼用溶液的影响,以及貯存期间发生混濁或霉败等。一般眼用溶液都採取以橡皮塞塞口、上大下小的玻瓶灌装。由于眼用溶液貯存期间的混濁变质与直接接触眼用溶液的包装材料有密切关系,固此有先对玻瓶及橡皮塞问题加以讨论的必要,然后再讨论制备环境与悬浮异物的来源等问题。
There are many problems with ophthalmic solution in mass production, such as the instability of hair mixing ratio, the incorporation of impurities, the effect of tool material on ophthalmic solution, and opacity or decay during storage. General ophthalmic solutions are taken to rubber stopper plug mouth, big glass bottle filling. Because ophthalmic solution storage during the turbid metamorphic and direct contact with the ocular solution packaging materials are closely related, so there is a first glass bottle and rubber plug to discuss the issue of necessity, and then discuss the preparation of the environment and the source of suspended foreign matter and other issues .