Screening the RFX6-DNA binding domain for potential genetic variants in patients with type 2 diabete

• 作 者: Ismail S Mahmoud Ayat Homsi Ha
• 机 构: DepartmentofMedicalLaboratorySciences,CellTherapyCentre,DepartmentofPharmacology
• 出 处: 世界糖尿病杂志:英文版(电子版)
• 发表日期: 2019年3期
• 关键词: REGULATORY factor X6 Genetic VARIANT DIABETES DNA BINDING DOMAIN

BACKGROUND The regulatory factor X6 (RFX6), a member of regulatory factor X family, is known to play a key role in the development and differentiation of pancreatic beta cells as well as insulin production and secretion. However, the potential role of RFX