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对４０例有ＨＢＶ感染证据但目前ＨＢｓＡｇ阴性的肝硬化患者进行临床，病原学及预后分析，并以ＨＢｓＡｇ阳性肝硬化作为对照组。结果ＨＢｓＡｇ阴性组血清胆红素（ＳＢ）升高、白蛋白下降，球蛋白增高和凝血酶原活动度下降者比率均低于对照组，但病毒血症，并发症发生率和经治好转率均与对照组相近。提示ＨＢｓＡｇ阴性的ＨＢＶ相关性肝硬化具有与对照组类似的传染性，尽管肝功指标较好，但病情隐匿进展，预后未能改善。
40 cases of patients with evidence of HBV infection but the current HBsAg-negative patients with cirrhosis clinical, etiological and prognostic analysis, and HBsAg positive cirrhosis as a control group. Results Serum bilirubin (SB) increased, serum albumin decreased, globulin increased and prothrombin activity decreased in HBsAg-negative group were lower than those in control group, but the incidence of viremia, complication rate and improvement rate Similar to the control group. It is suggested that HBsAg-negative HBV-related cirrhosis is similar to that of the control group. Although the liver function is better, the condition is hidden and the prognosis is not improved.