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作者通过总结22例中线非何杰金氏恶性淋巴瘤的临床、病理及免疫病理学特点,阐明其病变的本质是淋巴系统的一类恶性肿瘤。该病以上呼吸道鼻面等中线部位为其独特的发病部位,症状表现复杂,病理组织学表现为单一淋巴瘤样细胞的单形性和广泛坏死炎性肉芽组织中夹杂有数量不等的异形淋巴细胞的多形性两大类。22例中20例免疫组织化学染色结果T细胞性16例,B细胞性4例,据此可鉴别于具有类似临床表现,而无此病理与免疫病理学改变的疾病。
The authors summarize the clinical, pathological and immunopathological features of 22 cases of midline non-Hodgkin’s lymphoma, clarifying that the nature of the lesion is a type of malignant tumor of the lymphatic system. The disease in the upper respiratory tract and other midline nasal parts of its unique site of disease, the symptoms of complex histopathological manifestations of a single lymphoma-like cells and extensive necrosis of granulomatous mixed with an irregular number of shaped lymphocytes The polymorphism of two categories. Twenty-four cases of T cell and four cases of B cell were detected by immunohistochemical staining in 20 cases of 22 cases, which could be distinguished from those with similar clinical manifestations without such pathological and immunopathological changes.