论文部分内容阅读
结节病的治疗,迄今未曾令人满意。长期患者有发展成为进行性肺纤维化的危险。应用皮质激素治疗,常可导致症状立即缓解及肺部浸润消散。然而在多数病例,作用仅为抑制性的,且为时短暂,对于疾病的后果并无决定性的影响。作者观查到一例32岁女性患者,自24岁起患结节病。对其广泛性的肺部浸润应用皮质激素治疗,疗效不满意,但当患者静脉炎用抗凝治疗时,肺部浸润却完全消散。结节病的后果虽不能预测,然在少数情况下,如上述的一例甚至在病情活动8年后获得了完全彻底的治愈。因此应考虑到是抗凝治疗的有效作用。有关结节病的发病机理仍不明。但由于受该病侵袭器官的组织病理学表现有广泛性上皮样细胞肉芽肿
The treatment of sarcoidosis has so far not been satisfactory. Long-term patients have the risk of developing progressive pulmonary fibrosis. Application of corticosteroid treatment, often can lead to immediate relief of symptoms and lungs infiltration dissipated. In most cases, however, the effects are only inhibitory and transient and have no decisive effect on the consequences of the disease. The authors observed a 32-year-old woman who developed sarcoidosis from the age of 24. For its extensive pulmonary infiltration of corticosteroids, the effect is not satisfied, but when patients with phlebitis anticoagulant therapy, lung infiltration has completely dissipated. Although the consequences of sarcoidosis are unpredictable, in a few cases, a complete cure, such as the one above, is obtained even after 8 years of disease activity. Therefore, it should be considered that the effective role of anticoagulant therapy. The pathogenesis of sarcoidosis is still unknown. However, due to the invasion of organ disease histopathology showed widespread epithelioid cell granuloma