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AFM_1是AFB_1经多种动物代谢后的较重要的产物之一。在动物肝脏、尿液、粪便、乳中都有发现。自从发现AFM_1对动物致癌以来,认为牛乳中存在这一毒物对人健康是一个潜在危险。过去,因为没有适当的方法测定大鼠、小鼠小量乳样中的代谢物。用酶联免疫吸附法(ELISA)可检测25μl乳样中0.25ppb的
AFM_1 is one of the more important AFB_1 products metabolized by a variety of animals. In animal liver, urine, stool, milk are found. Since AFM_1 was found to be carcinogenic to animals, the presence of this poison in milk is considered to be a potentially dangerous human health. In the past, there was no suitable method to determine metabolites in small amounts of milk from mice and mice. Enzyme-linked immunosorbent assay (ELISA) can detect 0.25 ppb in 25 [mu] l of the milk sample