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目的:探讨补锌对婴幼儿迁延性腹泻患儿的临床疗效观察。方法:将87病例随机分为治疗组45例与对照组42例,2组病例治疗均包括纠正脱水、水电解质紊乱,加强营养支持,指导饮食治疗、对症治疗等。治疗组在此基础上加用1%硫酸锌(1ml含元素锌4mg)口服。结果:治疗组显效31例(68.9%),有效10例(22.2%),无效4例(4.7%)。对照组显效22例(52.3%),有效9例(21.4%),无效11例(26.2%)。治疗组与对照组总有效率分别为91.1%和73.7%,平均起效时间4.8天~7.2天。2者差异均有显著性意义。结论:对迁延性腹泻患儿口服硫酸锌0.5~1.0ml/kg/d.可以减轻迁延性腹泻症状,缩短病程。
Objective: To investigate the clinical effect of zinc supplementation on children with persistent diarrhea. Methods: Eighty-seven cases were randomly divided into treatment group (n = 45) and control group (n = 42). The treatment of two groups included correcting dehydration, water and electrolyte disturbance, enhancing nutrition support, guiding diet therapy and symptomatic treatment. On the basis of this treatment group, 1% zinc sulfate (1ml zinc 4mg) was added orally. Results: The treatment group markedly effective in 31 cases (68.9%), effective in 10 cases (22.2%), ineffective in 4 cases (4.7%). The control group was effective in 22 cases (52.3%), effective in 9 cases (21.4%), ineffective in 11 cases (26.2%). The total effective rate of the treatment group and the control group was 91.1% and 73.7% respectively, with an average onset time of 4.8 days to 7.2 days. 2 differences were significant. Conclusion: Oral administration of zinc sulfate 0.5-1.0ml / kg / d in children with persistent diarrhea can alleviate the symptoms of persistent diarrhea and shorten the course of the disease.