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目的观察米索前列醇联合缩宫素预防产后出血的疗效。方法将120例产后出血患者随机分为治疗组和对照组,治疗组在胎儿娩出后予米索前列醇直肠给药,并肌肉注射缩宫素;对照组仅肌肉注射缩宫素。观察并对比两组产后2 h出血量和第三产程时间等变化。结果治疗组产后2 h出血量和第三产程时间较对照组显著减少(P<0.01或P<0.05)。结论米索前列醇联合缩宫素能够有效加强宫缩,预防产后出血。
Objective To observe the effect of misoprostol combined with oxytocin in preventing postpartum hemorrhage. Methods 120 cases of postpartum hemorrhage were randomly divided into treatment group and control group. The treatment group received misoprostol rectally after delivery and intramuscular injection of oxytocin. The control group received only intramuscular injection of oxytocin. Observe and compare the two groups of postpartum 2 h bleeding and the third stage of labor time changes. Results The bleeding volume and the third stage of labor in the treatment group were significantly decreased 2 h postpartum as compared with the control group (P <0.01 or P <0.05). Conclusion Misoprostol combined with oxytocin can effectively enhance uterine contractions and prevent postpartum hemorrhage.