急性重度有机磷农药中毒致呼吸肌麻痹临床治疗体会

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目的观察急性重度AOPP致RMP的临床疗效。方法我科自2005年1月-2008年11月收治AOPP致RMP患者27例,早期合理应用盐酸戊乙奎醚(长托宁)与氯磷定。RMP一旦形成,立即行气管插管或气管切开,呼吸机辅助呼吸。结果27例患者中25例抢救成功,死亡2例,均为氧化乐果中毒。因患者服毒量过大,服毒时间过长,加之氯磷定剂量不足。结论对AOPP致RMP患者的治疗,合理应用长托宁、氯磷定,尽早机械通气,是救治成功的关键。 Objective To observe the clinical efficacy of acute severe AOPP-induced RMP. Methods From January 2005 to November 2008, our department admitted 27 cases of RMP caused by AOPP, and used penehyclidine hydrochloride (penehyclidine hydrochloride) and chlorpromazine rationally in the early stage. Once the RMP is formed, endotracheal or tracheostomy is performed immediately, and the ventilator assists breathing. Results Of the 27 patients, 25 cases were successfully treated and 2 died, all of which were omethoate. Due to patients with excessive drug load, taking too long, coupled with the lack of dose of chlorine phosphorus. Conclusion The treatment of AOPP induced RMP patients, the rational use of penehyclidine, chlorpromazine, mechanical ventilation as soon as possible, is the key to successful treatment.
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