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目的 :探讨儿童弓形虫脑炎的临床表现及治疗。方法 :对可疑患儿采用血或脑脊液查弓形虫循环抗原 (TCA) ,用酶联免疫吸附法 (ELSIA)测弓形虫抗体 ,TCA阳性者用磺胺嘧啶和乙酰螺旋霉素治疗。结果 :在TCA阳性的 5 6例中 ,发热 39例 ,头晕头痛 2 8例 ,呕吐 2 1例 ,抽搐 16例 ,脑膜刺激征阳性者 11例。结论 :获得性弓形虫脑炎临床表现复杂多样 ,轻重差别大 ,易于误诊 ,磺胺嘧啶及乙酰螺旋霉素治疗有良效。
Objective: To investigate the clinical manifestations and treatment of toxoplasma gondii in children. Methods: Toxoplasma gondii antigens (TCA) were detected in blood or cerebrospinal fluid (CSF) of suspicious children. Toxoplasma gondii antibody was detected by enzyme-linked immunosorbent assay (ELSIA) and treated with sulfadiazine and acetylspiramycin. Results: Among TCA positive cases, 39 cases were fever, 28 cases were dizzy and headache, 21 cases were vomiting, 16 cases were convulsions and 11 cases were positive for meningeal irritation. Conclusion: The clinical manifestation of acquired Toxoplasma gondii is complex and diverse with different severity, which is easy to misdiagnosis. The treatment with sulfadiazine and acetylspiramycin is effective.