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作者对应用5-氨基乙酰丙酸(ALA)光动力学(PDT)治疗Barrett食管的不典型增生和早期癌变初步经验进行了报道。 材料和方法 32例Barrett食管病人经组织学证实为重度不典型增生10例,早期食管粘膜癌22例。男24例,女8例,平均年龄68.5岁。搜集病人病史及体检资料,同时完成血细胞计数、血生化、尿液检查,并进行内窥镜、超声内镜、腹部超声、后前位和侧位荧光检查及胸、腹部CT扫描检查。分别于
The authors report the initial experience with the use of 5-aminolevulinic acid (ALA) photodynamic therapy (PDT) in the treatment of atypical hyperplasia and early cancers in Barrett’s esophagus. Materials and Methods 32 cases of Barrett’s esophagus were histologically confirmed as severe atypical hyperplasia in 10 cases and early esophageal mucosa in 22 cases. 24 males and 8 females, with an average age of 68.5 years. The patient’s medical history and physical examination data were collected. At the same time, hematocrit, blood biochemistry and urine tests were performed. Endoscopy, endoscopic ultrasonography, abdominal ultrasonography, posterior and lateral fluoroscopy, chest and abdomen CT scan were also performed. Respectively