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Objective: To retrospectively study the clinical effects of eardrum flap area on the healing outcome following traumatic perforation.Methods: Totally 291 traumatic eardrum perforations with in-/everted edges were included in this study. They were randomly divided into three groups and received conservative treatment, epidermal growth factor (EGF) via Gelfoam patching, or edge-approximation plus Gelfoam patching respectively. Patients in each group were further divided into two subgroups according to the eardrum flap area ≤ 1/2 or ＞1/2 of the perforation size. The healing rate and mean closure time after tympanic membrane perforation were evaluated at three months.Results: Of the total 291 participants, 281 were included in the final statistical analysis. The area of curled edge did not affect the healing outcome significantly in any groups (P＞0.05). The healing rate varied slightly: 90.7％ vs 92.3％ in spontaneous healing group, 98.2％ vs 97.4％ in EGF via Gelfoam patching group, and 96.5％ vs 100％ in edge-approximation plus Gelfoam patching group. In addition, in all groups the area of curled edge did not affect the mean closure time significantly (P＞0.05). The closure time was (32.3±2.4) d vs (30.6±3.1) d in sponaneous healing group, (13.4±2.5) d vs (13.1± 1.9) d in EGF via Gelfoam patching group, and (11.9±3.1) d vs (12.2±2.1) d in edge-approximation plus Gelfoam patching group.Conclusion: The eardrum flap area of traumatic eardrum perforation does not significantly affect the clinical outcomes.