论文部分内容阅读
本文应用放射免疫（RIA）和免疫放射（IRMA）方法对20例早孕妇女的人绒毛膜促性腺激素（hCG）水平进行了研究，以求阐明是否hCG具有垂体促甲状腺激素（TSH）样作用的可能性。结果显示，甲孕妇女四碘甲状腺原氨酸（T4）和游离甲状腺素（FT4）水平升高，hCG浓度与T4、FT4亦成正相关关系，然其三碘甲状腺原氨酸（T3）、游离三碘甲状腺原氨酸（FT3）水平却与正常对照组无明显差异。hCG水平升高与TSH水平下降成负相关关系（r＝－0．683，P＜0.001）。这些结果提示，早孕妇女，其甲状腺功能增强并非由垂体分泌的TSH刺激所致，而可能是受到另一种物质的刺激，即hCG促使甲状腺功能的增强所致。
In this paper, 20 cases of early pregnancy women’s human chorionic gonadotropin (hCG) levels were studied by radioimmunoassay (RIA) and immuno-radiation (IRMA) in order to clarify whether hCG has pituitary thyroid stimulating hormone (TSH) -like effects possibility. The results showed that the level of T4 and FT4 in the hypothyroidism increased and the concentration of hCG was also positively correlated with T4 and FT4. However, the triiodothyronine (T3), free Triiodothyronine (FT3) levels but no significant difference with the normal control group. There was a negative correlation between hCG level and TSH level (r = -0.683, P <0.001). These results suggest that in early pregnant women, thyroid function is not enhanced by TSH stimulated by pituitary secretion, but may be stimulated by another substance, that hCG promote thyroid function increased.