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目的采用Meta分析评价中国男男性行为者(MSM)队列保持状况及影响因素,为开展MSM队列研究提供依据。方法通过检索Pubmed、CNKI、万方数据库和维普数据库,收集2010-2016年10月发表的关于MSM队列保持的研究文献,并对纳入文献进行质量评价,应用Stata 12.0软件进行异质性检验及合并队列保持率,计算发表偏倚和进行敏感性分析。结果共16篇文献入选。Meta分析表明,合并之后中国MSM队列保持率为61.3%。当地居住时间[比值比(OR)=2.072,95%可信区间(CI):1.765~2.432]、既往HIV检测(OR=1.803,95%CI:1.568~2.073)、年龄(OR=1.806,95%CI:1.361~2.395)、文化程度(OR=1.962,95%CI:1.453~2.649)、本地户口(OR=2.714,95%CI:1.980~3.721)、参加6个月随访(OR=17.668,95%CI:8.050~38.779),是MSM队列保持的相关因素。结论中国MSM队列保持率为61.3%,当地居住时间长、既往做过HIV检测、年龄大、文化程度高、本地户口、参加6个月随访的MSM更容易完成队列随访。
Objective To evaluate the status of the cohort of Chinese men who have sex with men (MSM) and its influencing factors by Meta-analysis, and provide the basis for the study of MSM cohort. Methods We searched PubMed, CNKI, Wanfang database and VIP database to collect the research literature on MSM cohort preservation published in the period of October 2010 to October 2016. The quality of the included literature was evaluated and the heterogeneity was tested and merged using Stata 12.0 software Cohort retention, calculation of publication bias and sensitivity analysis. Results A total of 16 articles were selected. Meta-analysis showed that China’s MSM cohort retention rate was 61.3% after the merger. (OR = 1.803, 95% CI: 1.568 ~ 2.073), and age (OR = 1.806, 95% CI: 1.765-2.432) (OR = 2.714, 95% CI: 1.980 ~ 3.721), followed up for 6 months (OR = 17.668, 95% CI: 8.050 ~ 38.779), which is the relevant factor of MSM cohort. Conclusion The retention rate of Chinese MSM cohort was 61.3%. The long-term local residents lived in HIV-infected patients. The older MSM with high education, local residents and 6-month follow-up were more likely to complete cohort follow-up.