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对116例妊高征患者同时检测血液流变性、血管紧张素Ⅱ(angiotonimⅡ,AⅡ)、醛固酮(al-dosterome,ALD)及血管内皮素(endothelin,ET),并与100例正常孕晚期妇女作对照。结果提示:在妊高征患者中存在着三种不同情况:①血管紧张素Ⅱ增高;②醛固酮增高;③血管紧张素Ⅱ、醛固酮正常。应用无创性心血管血流参数检测见不同类型妊高征其血液动力学有着不同的改变。临床上根据监测指标作妊高征分型。采用不同治疗方法,高AⅡ型妊高征常有血液浓缩、低血容量,表现为低排高阻,可采用解痉、扩容治疗。醛固酮增高型妊高征呈低血粘度,常伴有血容量增加,心排出量增加,治疗以解痉、适当利尿,不需采用扩容治疗。
One hundred and sixty-six patients with PIH were tested for hemorrheology, angiotensin Ⅱ (AⅡ), aldosterone (ALD) and endothelin (ET) at the same time. Control. The results suggest that there are three different situations in patients with PIH: ① increased angiotensin Ⅱ; ② increased aldosterone; ③ angiotensin Ⅱ, normal aldosterone. The application of noninvasive cardiovascular blood flow parameters to detect different types of pregnancy-induced hypertension have different hemodynamic changes. Clinically based on monitoring indicators for pregnancy-induced syndromes. Different treatment methods, high A Ⅱ type of pregnancy-induced hypertension often have blood concentration, hypovolemia, showed low-row high resistance, can be used to spasm, dilatation treatment. Hyperaldosteronism-induced hypertension showed low blood viscosity, often accompanied by increased blood volume, increased cardiac output, treatment to antispasmodic, appropriate diuretic, without the use of dilatation and treatment.