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为明确妊娠母鼠添加饲喂叶黄素对初生仔鼠免疫功能的影响,对妊娠母鼠添加饲喂叶黄素后检测母鼠产前14 d内体质量变化、母鼠产前第14天至产后第14天日采食量变化、仔鼠出生后14 d内体质量变化以及出生第7天和第14天仔鼠血清、胃内容物和粪便中免疫球蛋白A(immunoglobulin A,Ig A)和免疫球蛋白G(Ig G)含量变化。结果表明:母鼠体质量、母鼠日采食量、仔鼠出生后6 d的体质量均没有显著变化(P>0.05);实验组仔鼠出生后7~14 d的体质量显著高于对照组(P<0.05);与对照组相比,实验组仔鼠出生第7天和第14天血清中和胃内容物中Ig G含量均显著升高(P<0.05,P<0.01),而粪便中Ig G含量与对照组无显著性差异(P>0.05);实验组仔鼠第7天和第14天胃内容物中Ig A含量极显著高于对照组(P<0.01),而血清和粪便中Ig A含量虽呈升高趋势,但与对照组无显著性差异(P>0.05)。实验结果说明给妊娠母鼠饲喂叶黄素可以增强初生仔鼠的免疫能力。
In order to clarify the effects of lutein supplementation on the immune function of newborn pups in pregnant rats, the changes of body weight of pregnant daughters during the 14th prenatal period were observed after adding lutein, The change of daily feed intake on the 14th day after delivery, the change of body weight of the offspring within 14 days after birth, and the immunoglobulin A (IgA) in the serum, stomach contents and feces of the offspring on the 7th and the 14th day after birth ) And immunoglobulin G (Ig G) content changes. The results showed that there was no significant change in body weight, daily feed intake, and body weight at 6 d after birth (P> 0.05). The body weight of pups in experimental group was significantly higher than that at 7 ~ 14 d after birth (P <0.05). Compared with the control group, the content of Ig G in serum and stomach contents in the experimental group was significantly increased on the 7th day and the 14th day (P <0.05, P <0.01) However, the content of Ig G in the feces was not significantly different from that in the control group (P> 0.05). The content of Ig A in the stomach contents of the seventh day and the fourteenth day in the experimental group was significantly higher than that in the control group (P <0.01) Serum and faecal IgA levels showed an upward trend, but no significant difference with the control group (P> 0.05). The experimental results show that feeding pregnant rats lutein can enhance the immune capacity of newborn pups.