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目的探讨血清超敏C反应蛋白(hsCRP)在冠心病诊断中的作用。方法 2010年5月至2012年5月期间,我院诊治的90例冠心病患者作为观察组研究对象,以同期体检中心的90例健康体检者作为对照组研究对象,通过免疫透射比浊法,测定两组患者血清超敏C反应蛋白的浓度,并进行比较。结果与对照组相比,观察组的超敏C反应蛋白水平明显升高,P<0.05;与稳定型心绞痛患者相比,不稳定型心绞痛、急性心肌梗死患者血清超敏C反应蛋白水平明显升高,P<0.05;与不稳定型心绞痛患者相比,急性心肌梗死患者血清超敏C反应蛋白水平明显升高,P<0.05。结果表明,随着病变程度的加重,血清超敏C反应蛋白水平明显升高。结论血清超敏C反应蛋白水平变化能够较为准确地反应冠心病的发生、发展程度,定期临床检测对于临床诊断,具有重要的临床意义。
Objective To investigate the role of serum hsCRP in the diagnosis of coronary heart disease. Methods From May 2010 to May 2012, 90 patients with coronary heart disease diagnosed and treated in our hospital were selected as the observation group. 90 healthy subjects in the same period as the control group were selected as the control group. By immunoturbidimetry, The concentrations of serum high-sensitivity C-reactive protein in both groups were determined and compared. Results Compared with the control group, the levels of hypersensitive C-reactive protein in the observation group were significantly increased (P <0.05). Compared with patients with stable angina, the levels of serum high-sensitivity C-reactive protein in patients with unstable angina and acute myocardial infarction were significantly increased High, P <0.05; Compared with patients with unstable angina, the level of serum high-sensitivity C-reactive protein was significantly increased in patients with acute myocardial infarction (P <0.05). The results showed that with the severity of the disease, the level of serum high-sensitivity C-reactive protein was significantly increased. Conclusions The change of serum high-sensitivity C-reactive protein can accurately reflect the occurrence and development of coronary heart disease. It is of great clinical significance to clinical diagnosis.