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用原代人胚肺成纤维细胞对新生儿肝炎综合症和患儿母亲28例,在尿液和宫颈分泌物中分离到巨细胞包涵体病毒12例,初步证实西宁地区巨细胞包涵体病毒是新生儿肝炎综合症的主要病原体之一,感染原来自母体。在妊娠中期或后期先天性感染的2例患儿表现为智力低下,发育受阻、耳聋、失明、神经系统和生理功能严重障碍,甚至死亡。在8例巨细胞包涵体病毒的患儿中5例续发肺炎,提示在新生儿肺炎中,巨细胞包涵体病毒性肺炎占有一定的数量。
With primary human embryo lung fibroblasts in neonates with hepatitis syndrome and 28 cases of mothers with children, in urine and cervical secretions isolated cytomegalovirus in 12 cases, initially confirmed Xining cytomegalovirus is One of the major pathogens of neonatal hepatitis syndrome, the original source of infection from the mother. Two cases of congenital infection in the second trimester of pregnancy showed mental retardation, impaired development, deafness, blindness, severe neurological and physical disorders, and even death. In 8 cases of cytomegalovirus in children with recurrent pneumonia in 5 cases, suggesting that in neonatal pneumonia, cytomegalovirus viral pneumonia occupy a certain number.