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测定了50例婴幼儿极期、恢复期、正常儿童超氧化物歧化酶(SOD)及血清脂质过氧化物(LPO)含量,结果显示:肺炎极期SOD活性明显低于正常对照组(P<0.01),血清LPO含量明显高于正常对照组(P<0.01),表明自由基参与了肺炎的病理生理过程。联合应用大剂量抗氧化剂维生素E和维生素C佐治婴幼儿肺炎10例,结果表明其临床治愈时间、SOD活性及LPO含量能较快恢复正常,提示在常规治疗基础上加用抗氧化剂治疗婴幼儿肺炎有助于肺炎的早日恢复。
The content of superoxide dismutase (SOD) and serum lipid peroxides (LPO) in 50 infants and infants in polar, convalescent and normal infants were determined. The results showed that the SOD activity at the anaphase of pneumonia was significantly lower than that of the normal control group (P <0.01). The serum LPO level was significantly higher than that of the normal control group (P <0.01), indicating that free radicals are involved in the pathophysiological process of pneumonia. The combination of high-dose vitamin E and vitamin C treatment of infantile pneumonia in 10 cases, the results showed that the clinical cure time, SOD activity and LPO content can quickly return to normal, suggesting that in addition to conventional treatment based on the use of antioxidants in the treatment of infantile pneumonia Helps for early recovery of pneumonia.